S Ananth Karumanchi Selected Research

Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)

3/2022	Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia.
1/2022	Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders.
10/2020	Lead exposure and association with angiogenic factors and hypertensive disorders of pregnancy.
1/2020	Total Versus Free Placental Growth Factor Levels in the Pathogenesis of Preeclampsia.
1/2019	Preeclampsia: Pathophysiology, Challenges, and Perspectives
1/2019	AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis.
7/2018	Angiogenic biomarkers in triage and risk for preeclampsia with severe features.
1/2018	Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis.
12/2017	Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) and Risk of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.
1/2017	Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes.

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S Ananth Karumanchi Research Topics

Disease

125	Pre-Eclampsia (Preeclampsia) 11/2022 - 03/2003
32	Hypertension (High Blood Pressure) 01/2022 - 03/2003
19	Proteinuria 01/2018 - 03/2003
10	Neoplasms (Cancer) 12/2018 - 01/2002
8	Hypoxia (Hypoxemia) 01/2019 - 10/2004
8	Inflammation (Inflammations) 12/2018 - 10/2008
7	Acute Kidney Injury (Acute Renal Failure) 07/2020 - 08/2012
6	Vascular Remodeling 01/2020 - 07/2009
6	Hemolysis 08/2019 - 06/2006
6	Fibrosis (Cirrhosis) 01/2019 - 06/2012
6	Chronic Kidney Failure (Chronic Renal Failure) 06/2015 - 11/2009
6	Sepsis (Septicemia) 11/2012 - 03/2006
5	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2022 - 03/2011
5	Heart Failure 01/2021 - 09/2011
5	Ischemia 01/2019 - 02/2010
5	Edema (Dropsy) 08/2017 - 02/2008
5	Eclampsia 08/2012 - 07/2006
5	Endotoxemia 10/2011 - 06/2006
4	Vitamin D Deficiency 01/2021 - 09/2011
4	HELLP Syndrome 08/2019 - 01/2007
4	Neoplasm Metastasis (Metastasis) 12/2018 - 04/2005
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2015 - 01/2007
4	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 10/2014 - 02/2004
4	Renal Cell Carcinoma (Grawitz Tumor) 07/2011 - 01/2002
3	Fetal Death 01/2022 - 11/2009
3	Chronic Renal Insufficiency 01/2022 - 02/2010
3	Lung Injury 10/2021 - 06/2011
3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021 - 03/2007
3	Birth Weight (Birth Weights) 07/2020 - 07/2004
3	Thrombocytopenia (Thrombopenia) 01/2018 - 05/2010
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 02/2009
3	Obesity 01/2017 - 07/2010
3	Perinatal Death 07/2016 - 08/2012
3	Kidney Diseases (Kidney Disease) 11/2014 - 09/2010
2	Aneuploidy (Aneuploid) 11/2022 - 04/2013
2	Uremia 01/2022 - 01/2015
2	Delirium 10/2021 - 10/2021
2	Cognitive Dysfunction 10/2021 - 10/2021
2	Infections 01/2021 - 11/2012
2	Placenta Accreta 01/2020 - 01/2020
2	Diabetes Mellitus 12/2019 - 02/2017
2	Hemolytic-Uremic Syndrome 08/2019 - 02/2012
2	Thyroid Neoplasms (Thyroid Cancer) 12/2018 - 10/2017
2	Anemia 02/2017 - 02/2010
2	Cardiomegaly (Heart Hypertrophy) 01/2017 - 09/2011
2	Pulmonary Edema 07/2016 - 08/2012
2	Cerebral Hemorrhage 07/2016 - 08/2012

Drug/Important Bio-Agent (IBA)

57	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 03/2022 - 03/2003
42	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2022 - 03/2003
32	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2019 - 03/2003
31	EndoglinIBA 01/2019 - 06/2006
27	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2004
19	Biomarkers (Surrogate Marker)IBA 03/2022 - 09/2006
18	Tyrosine (L-Tyrosine)FDA Link 08/2016 - 10/2005
17	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 03/2022 - 02/2004
13	Angiogenic ProteinsIBA 10/2016 - 06/2005
9	EnzymesIBA 07/2020 - 06/2006
9	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 12/2018 - 08/2005
9	CalciumIBA 01/2017 - 02/2004
8	Vitamin D FDA LinkGeneric 01/2021 - 11/2009
5	LigandsIBA 01/2022 - 12/2007
5	Complement System Proteins (Complement)IBA 01/2022 - 09/2010
5	Messenger RNA (mRNA)IBA 01/2020 - 08/2005
5	AlbuminsIBA 02/2017 - 03/2007
5	Uric Acid (Urate)IBA 02/2009 - 02/2004
4	Oxygen (Dioxygen)IBA 01/2022 - 01/2002
4	CytokinesIBA 10/2021 - 02/2010
4	Pharmaceutical PreparationsIBA 01/2021 - 08/2008
4	CreatinineIBA 12/2016 - 03/2007
4	AldosteroneIBA 02/2014 - 01/2011
3	Interleukin-6 (Interleukin 6)IBA 10/2021 - 02/2010
3	AntioxidantsIBA 01/2019 - 12/2011
3	Angiopoietin-2IBA 01/2019 - 03/2006
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 12/2018 - 06/2009
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 12/2010
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2018 - 04/2012
3	Erythropoietin FDA Link 02/2017 - 02/2010
3	Lipocalin-2IBA 01/2016 - 04/2005
3	LeptinIBA 11/2011 - 07/2010
3	AntibodiesIBA 10/2008 - 06/2006
2	DNA (Deoxyribonucleic Acid)IBA 11/2022 - 01/2018
2	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2017
2	Biological ProductsIBA 01/2021 - 12/2018
2	Blood Proteins (Serum Proteins)IBA 01/2020 - 04/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 05/2017
2	VemurafenibIBA 12/2018 - 10/2017
2	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2018 - 02/2014
2	FibrinIBA 08/2017 - 06/2016
2	Hemoglobins (Hemoglobin)IBA 02/2017 - 11/2013
2	Phosphotransferases (Kinase)IBA 11/2016 - 05/2012
2	GelsolinIBA 10/2016 - 05/2009
2	Dextran SulfateIBA 03/2016 - 08/2011
2	Angiotensin IIIBA 01/2016 - 05/2010

Therapy/Procedure

23	Therapeutics 05/2021 - 01/2002
3	Drug Therapy (Chemotherapy) 01/2022 - 11/2010
3	Renal Dialysis (Hemodialysis) 02/2017 - 11/2009
3	Ligation 01/2016 - 10/2008
2	Hysterectomy 01/2020 - 01/2014
2	Glycemic Control 02/2017 - 02/2014
2	Blood Component Removal (Apheresis) 03/2016 - 08/2011